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Michel Spina

President


President

 

 

 

 

 



Michel Spina, graduated in Medicine in Padova, PhD at the University of St.Andrews (Scotland), attended mostly to the study of the elastic tissue in animals and humans, particularly that of the wall of the aorta and the pulmonary artery in normal and pathological conditions. The biochemical, ultrastructural and physical approach enabled him to devise non-degradative methods for the isolation of intact ECM components in order to investigate their chemical composition as well as the structural organization and the biomechanical properties of the elastic tissue. He also investigated the expression and the degradation activity of some matrix mettalloproteinases (MMPs) in tumoral invasion. Recently his research activity has been devoted to devise procedures for non-degradative isolation and to the characterization of decellularized vascular ECM (from xenogenic aortic and pulmonary valves) devoid of calcification properties and suitable for tissue engineering of heart valves.

 

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  michele.spina@unipd.it  
       
       
       
     
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